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1

HCV-Induced Immune Responses Influence the Development of Operational Tolerance After Liver Transplantation in Humans

Bohne, F., Londono, M.-C., Benitez, C., Miquel, R., Martinez-Llordella, M., Russo, C., Ortiz, C., Bonaccorsi-Riani, E., Brander, C., Bauer, T., Protzer, U., Jaeckel, E., Taubert, R., Forns, X., Navasa

Journal:

Science Translational Medicine

Year:

2014

Language:

english

File:

PDF, 695 KB

english, 2014

2

ATG-Fresenius Treatment and Low-Dose Tacrolimus: Results of a Randomized Controlled Trial in Liver Transplantation

C. E. Benítez, I. Puig-Pey, M. López, M. Martínez-Llordella, J. J. Lozano, F. Bohne, M. C. Londoño, J. C. García-Valdecasas, M. Bruguera, M. Navasa, A. Rimola, A. Sánchez-Fueyo

Journal:

American Journal of Transplantation

Year:

2010

Language:

english

File:

PDF, 343 KB

english, 2010

3

Following clinical liver transplantation, the majority of circulating cells exhibiting donor MHC are “cross-dressed” not “passenger” leukocytes

Mastoridis, S., Sanchez-Fueyo, A., Martinez-Llordella, M.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 234 KB

english, 2018

4

Multiparametric Analysis of Circulating Exosomes and Other Small Extracellular Vesicles by Advanced Imaging Flow Cytometry

Mastoridis, Sotiris, Bertolino, Giuliana Minani, Whitehouse, Gavin, Dazzi, Francesco, Sanchez-Fueyo, Alberto, Martinez-Llordella, Marc

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 4.39 MB

english, 2018

5

Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo

Yadav, M., Louvet, C., Davini, D., Gardner, J. M., Martinez-Llordella, M., Bailey-Bucktrout, S., Anthony, B. A., Sverdrup, F. M., Head, R., Kuster, D. J., Ruminski, P., Weiss, D., Von Schack, D., Blue

Journal:

Journal of Experimental Medicine

Year:

2012

Language:

english

File:

PDF, 2.25 MB

english, 2012

6

Prospective multicenter clinical trial of immunosuppressive drug withdrawal in stable adult liver transplant recipients

Benítez, Carlos, Londoño, María-Carlota, Miquel, Rosa, Manzia, Tommaso-Maria, Abraldes, Juan G., Lozano, Juan-José, Martínez-Llordella, Marc, López, Marta, Angelico, Roberta, Bohne, Felix, Sese, Pilar

Journal:

Year:

2013

Language:

english

File:

PDF, 564 KB

english, 2013

7

Upregulation of miR-142-3p in Peripheral Blood Mononuclear Cells of Operationally Tolerant Patients with a Renal Transplant

Danger, R., Pallier, A., Giral, M., Martinez-Llordella, M., Lozano, J. J., Degauque, N., Sanchez-Fueyo, A., Soulillou, J.-P., Brouard, S.

Journal:

Journal of the American Society of Nephrology

Year:

2012

Language:

english

File:

PDF, 992 KB

english, 2012

8

In autoimmune hepatitis type 1 or the autoimmune hepatitis-sclerosing cholangitis variant defective regulatory T-cell responsiveness to IL-2 results in low IL-10 production and impaired suppression

Liberal, Rodrigo, Grant, Charlotte R., Holder, Beth S., Cardone, John, Martinez-Llordella, Marc, Ma, Yun, Heneghan, Michael A., Mieli-Vergani, Giorgina, Vergani, Diego, Longhi, Maria Serena

Journal:

Year:

2015

Language:

english

File:

PDF, 1.34 MB

english, 2015

9

Immunotolerance in Liver Transplantation

Mastoridis, Sotiris, Martinez-Llordella, Marc, Sanchez-Fueyo, Alberto

Journal:

Seminars in Liver Disease

Year:

2017

Language:

english

File:

PDF, 218 KB

english, 2017

10

Immunometabolism

Martinez-Llordella, Marc, Mastoridis, Sotiris

Journal:

Transplantation Journal

Year:

2017

Language:

english

File:

PDF, 950 KB

english, 2017

11

Interferon Sparing Directly Acting Antiviral (DAA) Therapy for HCV in Decompensated Cirrhosis: Natural Killer Cell (NK) Phenotype is Associated with Non-Response

Childs, K., Merritt, E., Swanson, W., Sanchez-Fueyo, A., Martinez-Llordella, M., Agarwal, K., Carey, I.

Journal:

Journal of Hepatology

Year:

2016

Language:

english

File:

PDF, 106 KB

english, 2016

12

Biomarkers and immunopathology of tolerance

Mastoridis, Sotiris, Martínez-Llordella, Marc, Sanchez-Fueyo, Alberto

Journal:

Current Opinion in Organ Transplantation

Year:

2016

Language:

english

File:

PDF, 214 KB

english, 2016

13

IL-2 Therapy Restores the Impaired Function of Regulatory T Cells Induced by Calcineurin Inhibitors in Liver Transplantation

Whitehouse, G., Gray, E., Mastoridis, S., Kodela, E., Sanchez-Fueyo, A., Martinez-Llordella, M.

Journal:

Journal of Hepatology

Year:

2016

Language:

english

File:

PDF, 49 KB

english, 2016

14

The capacity of persistent HCV infection to regulate alloreactive T cells responses is reversed following viral eradication

Merritt, E., Childs, K., Carey, I., Agarwal, K., Sanchez-Fueyo, A., Martinez-Llordella, M.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 47 KB

english, 2018

15

Peripheral phenotype and gene expression profiles of combined liver-kidney transplant patients

Dumontet, Erwan, Danger, Richard, Vagefi, Parsia A., Londoño, Maria-Carlota, Pallier, Annaïck, Lozano, Juan José, Giral, Magali, Degauque, Nicolas, Soulillou, Jean-Paul, Martínez-Llordella, Marc, Lee,

Journal:

Liver International

Year:

2016

Language:

english

File:

PDF, 1.77 MB

english, 2016

16

P890 SPECIFIC PHENOTYPE AND GENE EXPRESSION PROFILES OF COMBINED LIVER AND KIDNEY TRANSPLANTED PATIENTS IN PERIPHERAL BLOOD MONONUCLEAR CELLS

Dumontet, E., Danger, R., Vagefi, P., Londoño, M.-C., Pallier, A., Lozano, J.J., Giral, M., Degauque, N., Martínez-Llordella, M., Latournerie, M., Boudjéma, K., Dulong, J., Tarte, K., Soulillou, J.-P.

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 65 KB

english, 2014

17

Normothermic machine perfusion (NMP) inhibits proinflammatory responses in the liver and promotes regeneration

Jassem, Wayel, Xystrakis, Emmanuel, Ghnewa, Yasmeen G., Yuksel, Muhammed, POP, Oltin, Martinez-Llordella, Marc, Jabri, Yamen, Huang, Xiaohong, Lozano, Juan J., Quaglia, Alberto, Sanchez-Fueyo, Alberto

Journal:

Year:

2018

Language:

english

File:

PDF, 813 KB

english, 2018

18

Comparison of Transcriptional and Blood Cell-Phenotypic Markers Between Operationally Tolerant Liver and Kidney Recipients

J. J. Lozano, A. Pallier, M. Martinez-Llordella, R. Danger, M. López, M. Giral, M. C. Londoño, A. Rimola, J. P. Soulillou, S. Brouard, A. Sánchez-Fueyo

Journal:

American Journal of Transplantation

Year:

2011

Language:

english

File:

PDF, 274 KB

english, 2011

19

TRANSCRIPTIONAL PROFILING OF LIVER GRAFTS IN SPONTANEOUS OPERATIONAL TOLERANCE.

Bohne, F., Martinez-Llordella, M., Lozano, J. J., Lopez, M., Benitez, C., Miquel, R., Tisone, G., Rimola, A., Sanchez-Fueyo, A.

Journal:

Transplantation Journal

Year:

2010

Language:

english

File:

PDF, 284 KB

english, 2010

20

Molecular Characterization of Acute Cellular Rejection Occurring During Intentional Immunosuppression Withdrawal in Liver Transplantation

Bonaccorsi-Riani, E., Pennycuick, A., Londoño, M.-C., Lozano, J.-J., Benítez, C., Sawitzki, B., Martínez-Picola, M., Bohne, F., Martínez-Llordella, M., Miquel, R., Rimola, A., Sánchez-Fueyo, A.

Journal:

American Journal of Transplantation

Year:

2016

Language:

english

File:

PDF, 3.70 MB

english, 2016

21

Multiparameter Immune Profiling of Operational Tolerance in Liver Transplantation

M. Martínez-Llordella, I Puig-Pey, G. Orlando, M. Ramoni, G. Tisone, A. Rimola, J. Lerut, D. Latinne, C. Margarit, I. Bilbao, S. Brouard, M. Hernández-Fuentes, J. -P. Soulillou, A. Sánchez-Fueyo

Journal:

American Journal of Transplantation

Year:

2007

Language:

english

File:

PDF, 402 KB

english, 2007

22

Corrigendum: The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance

Waterfield, Michael, Khan, Imran S, Cortez, Jessica T, Fan, Una, Metzger, Todd, Greer, Alexandra, Fasano, Kayla, Martinez-Llordella, Marc, Pollack, Joshua L, Erle, David J, Su, Maureen, Anderson, Mark

Journal:

Nature Immunology

Year:

2014

Language:

english

File:

PDF, 98 KB

english, 2014

23

FRI-116-Capturing the complexities of the immune system in patients with advanced cirrhosis using a whole blood culture system reveals a robust inflammatory response to endotoxin stimulation

Kronsten, Victoria, Woodhouse, Charlotte, Lim, Tiong Yeng, Martinez-Llordella, Marc, Sanchez-Fueyo, Alberto, Shawcross, Debbie

Journal:

Journal of Hepatology

Year:

2019

File:

PDF, 198 KB

2019

24

Characterization of γδ T cell subsets in organ transplantation

Isabel Puig-Pey, Felix Bohne, Carlos Benítez, Marta López, Marc Martínez-Llordella, Federico Oppenheimer, Juan José Lozano, Juan González-Abraldes, Giuseppe Tisone, Antoni Rimola, Alberto Sánchez-Fuey

Journal:

Transplant International

Year:

2010

Language:

english

File:

PDF, 332 KB

english, 2010

25

Low Dose Interleukin-2 for Refractory Autoimmune Hepatitis

Lim, Tiong Y., Martinez-Llordella, Marc, Kodela, Elisavet, Gray, Elisabeth, Heneghan, Michael A., Sanchez-Fueyo, Alberto

Journal:

Year:

2018

Language:

english

File:

PDF, 755 KB

english, 2018

26

Self-antigen-Driven Activation Induces Instability of Regulatory T Cells during an Inflammatory Autoimmune Response

Bailey-Bucktrout, Samantha L., Martinez-Llordella, Marc, Zhou, Xuyu, Anthony, Bryan, Rosenthal, Wendy, Luche, Herve, Fehling, Hans J., Bluestone, Jeffrey A.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.02 MB

english, 2013

27

Emergent Transcriptomic Technologies and Their Role in the Discovery of Biomarkers of Liver Transplant Tolerance

Mastoridis, Sotiris, Martínez-Llordella, Marc, Sanchez-Fueyo, Alberto

Journal:

Frontiers in Immunology

Year:

2015

Language:

english

File:

PDF, 158 KB

english, 2015

28

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

Zhou, Xuyu, Bailey-Bucktrout, Samantha L, Jeker, Lukas T, Penaranda, Cristina, Martínez-Llordella, Marc, Ashby, Meredith, Nakayama, Maki, Rosenthal, Wendy, Bluestone, Jeffrey A

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 680 KB

english, 2009

29

IL-2 therapy preferentially expands adoptively transferred donor-specific Tregs improving skin allograft survival

Ratnasothy, Kulachelvy, Jacob, Jacintha, Tung, Sim, Boardman, Dominic, Lechler, Robert Ian, Sanchez Fueyo, Alberto, Martinez-Llordella, Marc, Lombardi, Giovanna

Journal:

American Journal of Transplantation

Year:

2019

Language:

english

File:

PDF, 885 KB

english, 2019

30

Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family

Hélène Bour-Jordan, Jonathan H. Esensten, Marc Martinez-Llordella, Cristina Penaranda, Melanie Stumpf, Jeffrey A. Bluestone

Journal:

Immunological Reviews

Year:

2011

Language:

english

File:

PDF, 442 KB

english, 2011

31

Ways Forward for Tolerance-Inducing Cellular Therapies- an AFACTT Perspective

ten Brinke, Anja, Martinez-Llordella, Marc, Cools, Nathalie, Hilkens, Catharien M. U., van Ham, S. Marieke, Sawitzki, Birgit, Geissler, Edward K., Lombardi, Giovanna, Trzonkowski, Piotr, Martinez-Cace

Journal:

Frontiers in Immunology

Year:

2019

Language:

english

File:

PDF, 685 KB

english, 2019

32

The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance

Waterfield, Michael, Khan, Imran S, Cortez, Jessica T, Fan, Una, Metzger, Todd, Greer, Alexandra, Fasano, Kayla, Martinez-Llordella, Marc, Pollack, Joshua L, Erle, David J, Su, Maureen, Anderson, Mark

Journal:

Nature Immunology

Year:

2014

Language:

english

File:

PDF, 1.23 MB

english, 2014

33

End-stage renal disease: Dual transplantation—the immunological role of the liver

Martinez-Llordella, Marc, Sanchez-Fueyo, Alberto

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2014

Language:

english

File:

PDF, 649 KB

english, 2014

34

Low-dose interleukin-2 expands the number of circulating regulatory T cells in patients with treatment-refractory autoimmune hepatitis

Lim, T.Y., Codela, E., Gray, E., Heneghan, M., Martinez-Llordella, M., Sanchez-Fueyo, A.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 95 KB

english, 2018

35

P1311 : Thril; pilot study evaluating the safety and efficacy profile of regulatory T cell therapy in liver transplant recipients

Whitehouse, G.P., Safinia, N., Rebollo-Mesa, I., Lowe, K., Thirkell, S., Fry, L., Androulidakis, A., Martinez-Llordella, M., Hope, A., Aluvihare, V., Fisher, C., Lechler, R., Heaton, N., Lombardi, G.,

Journal:

Journal of Hepatology

Year:

2015

Language:

english

File:

PDF, 172 KB

english, 2015

36

Successful expansion of functional and stable regulatory T cells for immunotherapy in liver transplantation

Safinia, Niloufar, Vaikunthanathan, Trishan, Fraser, Henrieta, Thirkell, Sarah, Lowe, Katie, Blackmore, Laura, Whitehouse, Gavin, Martinez-Llordella, Marc, Jassem, Wayel, Sanchez-Fueyo, Alberto, Lechl

Journal:

Year:

2016

Language:

english

File:

PDF, 2.29 MB

english, 2016

37

Immunological Predictors of Nonresponse to Directly Acting Antiviral Therapy in Patients With Chronic Hepatitis C and Decompensated Cirrhosis

Childs, Kate, Merritt, Elliot, Considine, Aisling, Sanchez-Fueyo, Alberto, Agarwal, Kosh, Martinez-Llordella, Marc, Carey, Ivana

Journal:

Open Forum Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 407 KB

english, 2017

38

Tracking Donor-Reactive T Cells

Martinez-Llordella, Marc, Lechler, Robert

Journal:

Transplantation Journal

Year:

2015

Language:

english

File:

PDF, 97 KB

english, 2015

39

The main determinant of circulating exosomal miRNA profile across a spectrum of patients with liver injury is the degree of liver failure

Mastoridis, S., Patel, V., Woodhouse, C., Martinez-Llordella, M., Sanchez-Fueyo, A.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 166 KB

english, 2018

40

CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell response

Martinez-Llordella, M., Esensten, J. H., Bailey-Bucktrout, S. L., Lipsky, R. H., Marini, A., Chen, J., Mughal, M., Mattson, M. P., Taub, D. D., Bluestone, J. A.

Journal:

Journal of Experimental Medicine

Year:

2013

Language:

english

File:

PDF, 3.87 MB

english, 2013

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